PGLYRP1/PGRP-S Products

Antibodies
PGLYRP1/PGRP-S Antibody
PGLYRP1/PGRP-S Antibody
NBP1-20962
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
PGLYRP1/PGRP-S Antibody
PGLYRP1/PGRP-S Antibody
AF2590
Species: Hu
Applications: WB, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
PGLYRP1/PGRP-S Overexpression ...
PGLYRP1/PGRP-S Overexpression Lysa...
H00008993-T01
Species: Hu
Applications: WB
PGLYRP1/PGRP-S Overexpression ...
PGLYRP1/PGRP-S Overexpression Lysa...
NBL1-14334
Applications: WB
Proteins
Recombinant Mouse PGLYRP1/PGR ...
Recombinant Mouse PGLYRP1/PGRP-S P...
2696-PG
Species: Mu
Applications: Bind
PGLYRP1/PGRP-S Recombinant Pr ...
PGLYRP1/PGRP-S Recombinant Protein...
NBP1-92261PEP
Species: Hu
Applications: AC
RNAi
PGLYRP1/PGRP-S RNAi
PGLYRP1/PGRP-S RNAi
H00008993-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1,2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia, and PGRP-Ib) define a new family of human pattern recognition molecules (3). PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood (4). PGRP-S is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein (5). However, PGRP-S may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 8993
Alternate Names
  • Peptidoglycan recognition protein short
  • PGLYRP
  • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein)
  • TAG7
  • PGRPSMGC126896
  • PGRP-SMGC126894
  • PGRPpeptidoglycan recognition protein
  • TNFSF3L
  • peptidoglycan recognition protein 1

PTMs for PGLYRP1/PGRP-S

Learn more about PTMs related to PGLYRP1/PGRP-S.

Cleavage

Bioinformatics Tool for PGLYRP1/PGRP-S

Discover related pathways, diseases and genes to PGLYRP1/PGRP-S. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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