PDE5A Products

Description

This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Bioinformatics

Entrez	8654 Human 171115 Rat
Uniprot	NP_001074.2 Human NP_236914.2 Human NP_246273.2; Human O76074 Human
Product By Gene ID	8654
Alternate Names	CGB-PDE cGMP-binding cGMP-specific 3'-5'-cyclic nucleotide phosphodiesterase cGMP-binding cGMP-specific phosphodiesterase cGMP-specific 3'-5'-cyclic phosphodiesterase cGMP-specific phosphodiesterase type 5A CN5A EC 3.1.4 EC 3.1.4.35 PDE5 PDE5A phosphodiesterase 5A, cGMP-specific phosphodiesterase isozyme 5

Research Areas for PDE5A

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism
Signal Transduction