PABPC4 Products

Antibodies
PABPC4 Antibody
PABPC4 Antibody
NB100-74594
Species: Hu, Mu, Po, Bv, Ca, GP, Mk, Pm
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PABPC4 Antibody
PABPC4 Antibody
NB100-74593
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
PABPC4 Antibody
PABPC4 Antibody
NBP2-13722
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PABPC4 Overexpression Lysate ...
PABPC4 Overexpression Lysate (Native)
NBP2-07951
Applications: WB
PABPC4 Overexpression Lysate ...
PABPC4 Overexpression Lysate (Dena...
H00008761-T01
Species: Hu
Applications: WB
Proteins
PABPC4 Recombinant Protein An ...
PABPC4 Recombinant Protein Antigen
NBP2-13722PEP
Species: Hu
Applications: AC
RNAi
PABPC4 RNAi
PABPC4 RNAi
H00008761-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 8761
Alternate Names
  • IPABP
  • Inducible poly(A)-binding protein
  • polyadenylate-binding protein 4
  • PABP4Activated-platelet protein 1
  • APP1FLJ43938
  • iPABPpoly(A)-binding protein, cytoplasmic 4 (inducible form)
  • APP-1PABP-4
  • Poly(A)-binding protein 4
  • poly(A) binding protein, cytoplasmic 4 (inducible form)

Bioinformatics Tool for PABPC4

Discover related pathways, diseases and genes to PABPC4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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