p67phox/NOXA2 Products

Description

NOXA2 encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein.

Bioinformatics

Product By Gene ID	4688
Alternate Names	autosomal 2 NADPH oxidase activator 2 NCF2 NCF-2 neutrophil cytosol factor 2 neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal2) neutrophil cytosolic factor 2 NOXA2 NOXA2FLJ93058 p67phox p67-phox

Research Areas for p67phox/NOXA2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Immunology