p53R2 Products

Antibodies
p53R2 Antibody
p53R2 Antibody
NBP1-76781
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
p53R2 Antibody
p53R2 Antibody
AF3788
Species: Hu
Applications: WB
Host: Goat Polyclonal
p53R2 Antibody
p53R2 Antibody
NBP2-19668
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
p53R2 Overexpression Lysate ( ...
p53R2 Overexpression Lysate (Native)
NBP2-11462
Applications: WB
Proteins
p53R2 Partial Recombinant Pro ...
p53R2 Partial Recombinant Protein
H00050484-Q01
Species: Hu
Applications: WB, ELISA, PA
p53R2 Recombinant Protein Ant ...
p53R2 Recombinant Protein Antigen
NBP1-87368PEP
Species: Hu
Applications: AC
p53R2 Peptide
p53R2 Peptide
NBP1-76781PEP
Species: Hu
Applications: AC
RNAi
p53R2 RNAi
p53R2 RNAi
H00050484-R01
Species: Hu

Description

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumour suppression.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 50484
Alternate Names
  • PEOA5
  • MTDPS8A
  • ribonucleoside-diphosphate reductase subunit M2 B
  • EC 1.17.4.1
  • p53-inducible ribonucleotide reductase small subunit 2 homolog
  • TP53-inducible ribonucleotide reductase M2 B
  • MGC42116
  • p53-inducible ribonucleotide reductase small subunit 2-like protein
  • MGC102856
  • p53R2
  • P53R2DKFZp686M05248
  • MTDPS8B
  • ribonucleotide reductase M2 B (TP53 inducible)

Research Areas for p53R2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Checkpoint signaling
DNA Double Strand Break Repair
DNA Repair
Hypoxia
Modulation of DNA Pools
Phospho-Specific

PTMs for p53R2

Learn more about PTMs related to p53R2.

Phosphorylation
Methylation
Dephosphorylation
Ubiquitination

Bioinformatics Tool for p53R2

Discover related pathways, diseases and genes to p53R2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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