ORP150/HSP12A Products

Antibodies
ORP150/HSP12A Antibody
ORP150/HSP12A Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
ORP150/HSP12A Antibody (6F7)
ORP150/HSP12A Antibody (6F7)
H00010525-M01
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
ORP150/HSP12A Antibody
ORP150/HSP12A Antibody
NBP2-14113
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ORP150/HSP12A Overexpression ...
ORP150/HSP12A Overexpression Lysat...
H00010525-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human ORP150/HSP1 ...
Recombinant Human ORP150/HSP12A Pr...
H00010525-P02
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ORP150/HSP1 ...
Recombinant Human ORP150/HSP12A Pr...
H00010525-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human ORP150/HSP1 ...
Recombinant Human ORP150/HSP12A Pr...
H00010525-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ORP150/HSP12A RNAi
ORP150/HSP12A RNAi
H00010525-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HYOU1 is encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment is found at the 5' end of the first exon, and is involved in stress-dependent induction. A transcript that is produced from a downstream start site is preferentially induced by hypoxia, resulting in the accumulation of this protein in the endoplasmic reticulum (ER). The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 10525
Alternate Names
  • ORP-150
  • GRP170
  • GRP-170
  • oxygen regulated protein (150kD)
  • 170 kDa glucose-regulated protein
  • hypoxia up-regulated protein 1
  • 150 kDa oxygen-regulated protein
  • glucose-regulated protein 170
  • HSP12A
  • FLJ97572
  • Grp170
  • ORP150FLJ94899
  • DKFZp686N08236
  • hypoxia up-regulated 1

Research Areas for ORP150/HSP12A

Find related products by research area and learn more about each of the different research areas below.

Hypoxia

PTMs for ORP150/HSP12A

Learn more about PTMs related to ORP150/HSP12A.

Phosphorylation
Biotinylation
Oxidation

Bioinformatics Tool for ORP150/HSP12A

Discover related pathways, diseases and genes to ORP150/HSP12A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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