Optineurin Products

Description

Optineurin encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Bioinformatics

Uniprot	AAH13876 Human AAH32762 Human NM_001008211 Human NP_001008212 Human NP_001008212.1 Human NP_001008213 Human NP_001008214 Human NP_068815 Human NP_068815.2 Human Q96CV9 Human
Product By Gene ID	10133
Alternate Names	FIP2FIP-2 GLC1Eglaucoma 1, open angle, E (adult-onset) HIP7ALS12 Huntingtin interacting protein L Huntingtin yeast partner L Huntingtin-interacting protein 7 Huntingtin-interacting protein L HYPLHIP-7 NEMO-related protein NRPE3-14.7K-interacting protein Optic neuropathy-inducing protein optineurin TFIIIA-IntP TFIIIA-INTP Transcription factor IIIA-interacting protein transcrption factor IIIA-interacting protein tumor necrosis factor alpha-inducible cellular protein containing leucinezipper domains

Research Areas for Optineurin

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Vision