Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Pm-Or
Applications: WB, ICC/IF, IP, KD
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 (PubMed 1570339)).(supplied by OMIM)
Bioinformatics
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
4836 |
| Alternate Names |
- alternative, short form NMT-S
- glycylpeptide N-tetradecanoyltransferase 1
- long form, NMT-L
- Myristoyl-CoA:protein N-myristoyltransferase 1
- NMT 1
- NMTEC 2.3.1.97
- N-myristoyltransferase 1
- Peptide N-myristoyltransferase 1
- Type I N-myristoyltransferase
|
