NMT1 Products

Description

Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 (PubMed 1570339)).(supplied by OMIM)

Bioinformatics

Uniprot	P30419 Human NM_021079 Human NP_066565 Human NP_066565.1 Human
Product By Gene ID	4836
Alternate Names	long form, NMT-L Type I N-myristoyltransferase glycylpeptide N-tetradecanoyltransferase 1 Peptide N-myristoyltransferase 1 alternative, short form NMT-S Myristoyl-CoA:protein N-myristoyltransferase 1 NMTEC 2.3.1.97 NMT 1 N-myristoyltransferase 1

Diseases related to NMT1

Discover more about diseases related to NMT1.

Growth Arrest
Immunologic Deficiency Syndromes
Malignant Neoplasms
Hiv Infections
Carcinoma
Headache
Neoplasms
Mycoses
Candidiasis
Infective Disorder
Cell Transformation, Neoplastic
Malignant Tumor Of Colon
Adenocarcinoma
Colonic Neoplasms
Colorectal Cancer
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Cytomegalovirus Infections
Chromosome Breakage

Pathways for NMT1

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Localization
Cell Proliferation
Transport
Meiosis
Mating
Secretion
Mitosis
Cell Growth
Cell Division
Oncogenesis
Secretory Pathway
Dna Replication
S Phase
Regulation Of Gene Expression
Cell Cycle Arrest
Translation
Protein Myristoylation
Cell Death
Negative Regulation Of Cell Proliferation

PTMs for NMT1

Learn more about PTMs related to NMT1.

Myristoylation
Acylation
Phosphorylation
Oxidation
Hydroxylation
Cleavage
Methylation
Dephosphorylation
Ribosylation
Ubiquitination

Bioinformatics Tool for NMT1

Discover related pathways, diseases and genes to NMT1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.