Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
Species: Hu, Mu, Rb
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs tothe NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innateimmune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates thepro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as amultifunctional negative regulator of inflammation and apoptosis. (provided by RefSeq)
Bioinformatics
| Uniprot |
Human
Human
|
| Product By Gene ID |
338322 |
| Alternate Names |
- CLR11.1
- NACHT, leucine rich repeat and PYD containing 10
- NALP10Pynod
- NLR family, pyrin domain containing 10
- NOD8Nucleotide-binding oligomerization domain protein 8
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 10
- PAN5
- PYNODNACHT, LRR and PYD domains-containing protein 10
|
