NIPBL Products

Antibodies
NIPBL Antibody
NIPBL Antibody
NBP1-85110
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
NIPBL Antibody (3B9)
NIPBL Antibody (3B9)
H00025836-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
NIPBL Antibody
NIPBL Antibody
NBP1-77974
Species: Hu
Applications: WB, ELISA
Host: Goat Polyclonal
Proteins
NIPBL Partial Recombinant Pro ...
NIPBL Partial Recombinant Protein
H00025836-Q01
Species: Hu
Applications: WB, ELISA, PA
NIPBL Recombinant Protein
NIPBL Recombinant Protein
H00025836-P01
Species: Hu
Applications: WB, ELISA, PA
NIPBL Recombinant Protein Ant ...
NIPBL Recombinant Protein Antigen
NBP1-85110PEP
Species: Hu
Applications: AC
RNAi
NIPBL RNAi
NIPBL RNAi
H00025836-R02
Species: Hu
NIPBL RNAi
NIPBL RNAi
H00025836-R01
Species: Hu

Description

NIPBL encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and mental retardation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 25836
Alternate Names
  • SCC2 homolog
  • Delangin
  • Scc2
  • sister chromatid cohesion 2 homolog
  • FLJ13648
  • nipped-B-like protein
  • FLJ13354
  • delangin
  • FLJ12597
  • IDN3-B
  • FLJ11203
  • FLJ44854
  • DKFZp434L1319
  • IDN3CDLS
  • CDLS1
  • Nipped-B homolog (Drosophila)

Research Areas for NIPBL

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for NIPBL

Learn more about PTMs related to NIPBL.

Acetylation
Methylation
Deacetylation
Cleavage

Bioinformatics Tool for NIPBL

Discover related pathways, diseases and genes to NIPBL. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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