Neurotrypsin Products

Antibodies
Neurotrypsin Antibody
Neurotrypsin Antibody
NBP1-76784
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Neurotrypsin Antibody
Neurotrypsin Antibody
NBP1-03232
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Neurotrypsin Antibody
Neurotrypsin Antibody
NBP1-89925
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Neurotrypsin Overexpression L ...
Neurotrypsin Overexpression Lysate...
H00008492-T01
Species: Hu
Applications: WB
Proteins
Neurotrypsin Partial Recombin ...
Neurotrypsin Partial Recombinant P...
H00008492-Q01
Species: Hu
Applications: WB, ELISA, PA
Neurotrypsin Recombinant Prot ...
Neurotrypsin Recombinant Protein A...
NBP2-38231PEP
Species: Hu
Applications: AC
Neurotrypsin Recombinant Prot ...
Neurotrypsin Recombinant Protein A...
NBP1-89925PEP
Species: Hu
Applications: AC
RNAi
Neurotrypsin RNAi
Neurotrypsin RNAi
H00008492-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. There are three sequences published for neurotrypsin to date; 875, 834 and 505 amino acids in length. The predicted masses are 97, 92.5 and 55.7 kDa respectively, with predicted pI of 9.14, 8.88 and 6.57. The three forms all start at the same place. The 505 residue form terminates in the last SRCR domain, before the catalytic domain, and the 834 amino acid form has a 40 amino acid deletion that starts just after the PC site, and includes the catalytic histidine, thus both species would be proteolytically inactive.

Bioinformatics

Uniprot Human
Human
Human
Product By Gene ID 8492
Alternate Names
  • leydin
  • EC 3.4.21
  • brain-specific serine protease 3
  • Serine protease 12
  • MGC12722
  • Motopsin
  • BSSP3
  • Leydin
  • BSSP-3
  • MRT1EC 3.4.21.-
  • neurotrypsin
  • protease, serine, 12 (neurotrypsin, motopsin)

Diseases related to Neurotrypsin

Discover more about diseases related to Neurotrypsin.

Nervousness
Cell Invasion
Influenza
Anxiety Disorders
Malnutrition
Inflammation

Pathways for Neurotrypsin

View related products by pathway and learn more about each of the pathways below.

Localization
Drug Resistance
Long-term Memory
Glycosylation
Rna Interference

Research Areas for Neurotrypsin

Find related products by research area and learn more about each of the different research areas below.

Vision

PTMs for Neurotrypsin

Learn more about PTMs related to Neurotrypsin.

Phosphorylation
Glycosylation

Bioinformatics Tool for Neurotrypsin

Discover related pathways, diseases and genes to Neurotrypsin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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