Neuregulin-3/NRG3 Products

Neuregulin-3/NRG3 Antibody
Neuregulin-3/NRG3 Antibody
Species: Mu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Neuregulin-3/NRG3 Antibody
Neuregulin-3/NRG3 Antibody
Species: Hu, Mu, Rt
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Neuregulin-3/NRG3 Antibody
Neuregulin-3/NRG3 Antibody
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal


NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization.


Uniprot Human
Product By Gene ID 10718
Alternate Names
  • neuregulin 3 variant 4
  • Pro-NRG3
  • neuregulin 3 variant 3
  • pro-neuregulin-3, membrane-bound isoform
  • neuregulin 3 variant 14
  • pro-NRG3
  • neuregulin 3 variant 13
  • neuregulin-3-like polypeptide
  • neuregulin 3 variant 12
  • neuregulin 3 variant 9
  • neuregulin 3 variant 11
  • neuregulin 3 variant 8
  • neuregulin 3 variant 10
  • neuregulin 3 variant 7
  • neuregulin 3 variant 1
  • neuregulin 3 variant 6
  • HRG3
  • neuregulin 3 variant 5
  • neuregulin 3

PTMs for Neuregulin-3/NRG3

Learn more about PTMs related to Neuregulin-3/NRG3.


Bioinformatics Tool for Neuregulin-3/NRG3

Discover related pathways, diseases and genes to Neuregulin-3/NRG3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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