NDFIP2 Products

Description

NDFIP2, also known as NEDD4 family-interacting protein 2, NEDD4 WW domain-binding protein 5A, putative MAPK-activating protein PM04/PM05/PM06/PM07 and putative NF-kappa-B-activating protein 413, is a member of the Nedd4 family. NDFIP2 activates the HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2. NDFIP2 also recruits ITCH, NEDD4, and SMURF2 to endosomal membranes. NDFIP2 may also play a role in modulating EGFR signaling and other cellular processes.

Bioinformatics

Uniprot	NP_061953 Human Q9NV92 Human AAH21988 Human AAH26126 Human AAH26126.1 Human
Product By Gene ID	54602
Alternate Names	N4wbp5a NF-kappa-B-activating protein 413 NEDD4 WW domain-binding protein 5A NEDD4 family-interacting protein 2 Putative NF-kappa-B-activating protein 413 MAPK-activating protein PM04 PM05 PM06 PM07 KIAA1165N4WBP5APutative MAPK-activating protein PM04/PM05/PM06/PM07 FLJ25842 Nedd4 family interacting protein 2

Diseases related to NDFIP2

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Atresia
Anemia
Hypochromic Anemia
Iron Overload
Diabetes Mellitus
Immunologic Deficiency Syndromes
Iron Deficiency Anemia
Inflammatory Disorder
Hypertensive Disease
Renal Hypertension
Asthma
Diabetes Mellitus, Insulin-dependent
Inflammation
Iron Deficiency
Acute Interstitial Pneumonia

Pathways for NDFIP2

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Transport
Pathogenesis
Receptor-mediated Endocytosis
Cell Activation
Vesicle Transport
T Cell Activation
Endocytosis
Neuron Development
Ovulation
Sexual Reproduction
Oocyte Development
Cytoplasmic Transport
Biological Regulation
Cell Differentiation
Excretion

Research Areas for NDFIP2

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Signal Transduction

PTMs for NDFIP2

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Ubiquitination
Phosphorylation

Bioinformatics Tool for NDFIP2

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