NCOA6 Products

Antibodies
NCOA6 Antibody
NCOA6 Antibody
NB200-335
Species: Hu, Rt
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
NCOA6 Antibody
NCOA6 Antibody
NBP1-89193
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
NCOA6 Antibody
NCOA6 Antibody
NB200-336
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Proteins
Recombinant Human NCOA6 GST ( ...
Recombinant Human NCOA6 GST (N-Ter...
H00023054-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
NCOA6 Recombinant Protein Ant ...
NCOA6 Recombinant Protein Antigen
NBP1-89193PEP
Species: Hu
Applications: AC
NCOA6 Recombinant Protein Ant ...
NCOA6 Recombinant Protein Antigen
NBP2-55622PEP
Species: Hu
Applications: AC

Description

Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins. Involved in placental, cardiac, hepatic and embryonic development. NCOA6 is over-expressed in several breast cancer cell lines.

Bioinformatics

Uniprot Human
Human
Product By Gene ID 23054
Alternate Names
  • Activating signal cointegrator 2
  • AIB3NRC RAP250
  • Amplified in breast cancer protein 3
  • ASC-2
  • Cancer-amplified transcriptional coactivator ASC-2
  • KIAA0181PPAR-interacting protein
  • NRCamplified in breast cancer-3 protein
  • nuclear receptor coactivator 6
  • Nuclear receptor coactivator RAP250
  • Nuclear receptor-activating protein, 250 kDa
  • peroxisome proliferator-activated receptor interacting protein
  • PRIPPeroxisome proliferator-activated receptor-interacting protein
  • RAP250Thyroid hormone receptor-binding protein
  • thyroid hormone receptor binding protein
  • TRBPASC2activating signal cointegrator-2

Research Areas for NCOA6

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Cycle and Replication
DNA Repair
Phospho-Specific
Transcription Factors and Regulators
Tumor Suppressors

Bioinformatics Tool for NCOA6

Discover related pathways, diseases and genes to NCOA6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related NCOA6 Blog Posts

Check out the latest blog posts on NCOA6.
ASC-2: An important co-activator of different nuclear receptors
ASC-2, also known as Nuclear Receptor Co-Activator 6, directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. It is involved in the co-activation of different nuclear receptors, such as for steroi...    Read more.
Read more NCOA6 related blogs.