N-Cadherin Products

Antibodies
N-Cadherin Antibody [Unconjug ...
N-Cadherin Antibody [Unconjugated]
AF6426
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, ICC
Host: Sheep Polyclonal
Conjugate Catalog # Availability Size Price
N-Cadherin Antibody
N-Cadherin Antibody
NB200-592
Species: Hu, Mu, Rt, Am, Av, Bv, Ca, Ch, Fi, Rb, Xp
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Lysates
N-Cadherin Overexpression Lys ...
N-Cadherin Overexpression Lysate (...
NBL1-09030
Applications: WB
Proteins
N-Cadherin Partial Recombinan ...
N-Cadherin Partial Recombinant Pro...
H00001000-Q01
Species: Hu
Applications: WB, ELISA, PA
N-Cadherin Recombinant Protei ...
N-Cadherin Recombinant Protein Ant...
NBP2-38856PEP
Species: Hu
Applications: AC
RNAi
N-Cadherin RNAi
N-Cadherin RNAi
H00001000-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Cadherins are members of a multigene family of single chain glycoprotein receptors mediating Ca++-dependent cell-cell adhesion.1,2,3 The N-terminal part of these molecules is exposed on the external cell surface and contains the putative homophilic binding sites. This is followed by a typical single transmembrane sequence and usually, a cytoplasmic C-terminal tail4 which mediates interaction with the microfilament system through molecules such as catenins, plakoglobin, vinculin, and a-actinin. Cadherins which are primarily located in areas of cell-cell contacts, are involved in selective cell sorting and in the mechanical cytoplasmic response. They are implicated in morphogenetic processes, intercellular signalling and tumor invasiveness and metastasis. Multiple cadherins were characterized from diverse species and tissues including E-Cadherin, N-Cadherin (A-CAM), P-Cadherin, V-Cadherin, R-Cadherin and T-Cadherin. Specific antibodies against a highly conserved sequence from the cytoplasmic C-terminal of N-Cadherin have been prepared.5,6

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 1000
Alternate Names
  • cadherin 2, N-cadherin (neuronal)
  • CD325 antigen
  • CDw325
  • N-cadherin
  • Neural cadherin
  • neural-cadherin
  • CD325
  • NCADN-cadherin 1
  • CDHNcalcium-dependent adhesion protein, neuronal
  • cadherin-2
  • cadherin 2, type 1, N-cadherin (neuronal)

Research Areas for N-Cadherin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Cellular Markers
Extracellular Matrix
Phospho-Specific
Plasma Membrane Markers
Signal Transduction

Bioinformatics Tool for N-Cadherin

Discover related pathways, diseases and genes to N-Cadherin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related N-Cadherin Blog Posts

Check out the latest blog posts on N-Cadherin.
Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.
CD63: is it pro-metastatic or anti-metastatic?
CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several cellular signaling cascades along with acting as TIMP1 receptor. It is expressed by activated platelets, monocytes,...    Read more.
MMP24 (Matrix metalloproteinase-24, matrix metalloproteinase-25, MT5-MMP)
MMP24 is an extracellular matrix (ECM) degradative peptidase enzyme that is a member of the large family of matrix metalloproteinases (MMP). Each MMP has a different substrate specificity, and the aberrant or derailed expression of these is strongly c...    Read more.
Read more N-Cadherin related blogs.