MYH7 Products

Antibodies
MYH7 Antibody (2021A) [Unconj ...
MYH7 Antibody (2021A) [Unconjugated]
MAB90961
Species: Hu
Applications: WB, ICC
Host: Rabbit Monoclonal
MYH7 Antibody
MYH7 Antibody
NBP2-52737
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MYH7 Antibody (940906) [Uncon ...
MYH7 Antibody (940906) [Unconjugated]
MAB9096
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Proteins
Recombinant Human MYH7 Protei ...
Recombinant Human MYH7 Protein
H00004625-Q01
Species: Hu
Applications: WB, ELISA, PA
MYH7 Recombinant Protein Anti ...
MYH7 Recombinant Protein Antigen
NBP2-52737PEP
Species: Hu
Applications: AC
RNAi
MYH7 RNAi
MYH7 RNAi
H00004625-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

MYH7, also known as Myosin-7, is a 1,935 amino acid protein that is 223 kDa, found predominantly in myocytes and mediates plus-ended movement along microfilaments, it is involved in muscle contraction through cyclic interactions with actin-rich thin filaments, creating a contractile force. It is regulated by phosphorylation via myosin light chain kinase (MLCK) and by intracellular Ca2+ concentrations. Disease research is currently being studied with relation to this protein and myopathy, hypertrophic cardiomyopathy, familial hypertrophic cardiomyopathy, dilated cardiomyopathy, wolff-parkinson-white syndrome, left ventricular noncompaction, left ventricular noncompaction 5, long qt syndrome, endocardial fibroelastosis, scapuloperoneal syndrome, laing distal myopathy, rhabdomyosarcoma oculopharyngeal muscular dystrophy, ebstein anomaly, acute myocardial infarction, muscular dystrophy, myotonic dystrophy, and myocardial infarction. Its involvement has been observed with relation to YWHAQ, MYH13, MYL3, YWHAZ, MYH9, ACTB, NTHL1, and over 100 other proteins in cell adhesion integrin-mediated cell adhesion and migration, cell adhesion tight junctions, cytoskeleton remodeling regulation of actin cytoskeleton by Rho GTPases, immune response CCR3 signaling in eosinophils, development MAG-dependent inhibition of neurite outgrowth, RhoA pathway, factors promoting cardiogenesis in vertebrates, antioxidant action of vitamin-C, transendothelial migration of leukocytes, actin nucleation by ARP-WASP complex, cardiac muscle contraction, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy, and viral myocarditis pathways.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 4625
Alternate Names
  • MyHC-slow
  • SPMM
  • MyHC-beta
  • SPMD
  • rhabdomyosarcoma antigen MU-RMS-40.7A
  • MPD1
  • myosin-7
  • CMH1
  • myosin heavy chain (AA 1-96)
  • MYHCB
  • myhc-slow
  • cardiac muscle beta isoform
  • myosin, heavy polypeptide 7, cardiac muscle, beta
  • MGC138378
  • myopathy, distal 1
  • CMD1SMGC138376
  • DKFZp451F047
  • myosin, heavy chain 7, cardiac muscle, beta

PTMs for MYH7

Learn more about PTMs related to MYH7.

Phosphorylation
Cleavage

Bioinformatics Tool for MYH7

Discover related pathways, diseases and genes to MYH7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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