MS4A6A Products

Description

Chimera RNA interference (chimera RNAi) is process by which small interfering RNA/DNA chimera triggers the destruction of mRNA for the original gene.  The discovery work, design, and application of chimera RNAi has been pioneered by Professor Kaoru Saigo and Dr. Kumiko Ui-Tei at the University of Tokyo.  Chimera RNAi has many advantages over the conventional siRNAs.  First, it has been demonstrated to have reliable knock-down for over 10,000 human genes.  Because the human genome is composed of an intricate, genetic network, chimera RNAi's unique design has successfully obviated the off-target effects including microRNA-based influence.  Another advantage of the chimera RNAi technology is its effectiveness at low concentrations (0.5nM to 5nM); only mRNA is destroyed so genomic genes are not affected.  Finally, having both the sense and anti-sense strands consisting RNA/DNA chimera, it offers much greater compound stability for streamlining in vitro and in vivo assays and applications while minimizing interferon induction and other adverse reactions.

Bioinformatics

Product By Gene ID	64231
Alternate Names	4SPAN3 CD20 antigen-like 3 CD20L3 CD20L3MS4A6A-polymorph CD20-like precusor CDA01 Four-span transmembrane protein 3 four-span transmembrane protein 3.1,4SPAN3.2 four-span transmembrane protein 3.2 HAIRB-iso membrane-spanning 4-domains subfamily A member 6A membrane-spanning 4-domains, subfamily A, member 6A MGC131944 MGC22650 MS4A6A MS4A6MST090 MST090 MSTP090

Research Areas for MS4A6A

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Signal Transduction