MRCK Products

Description

MRCK is encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Bioinformatics

Entrez	114116 Rat 226751 Mouse 8476 Human
Uniprot	NP_003598 Human NP_055641 Human NP_055641.3 Human
Product By Gene ID	8476
Alternate Names	CDC42 binding protein kinase alpha (DMPK-like) CDC42 binidng protein kinase beta CDC42-binding protein kinase alpha (DMPK-like) CDC42-binding protein kinase alpha DMPK-like alpha EC 2.7.11 EC 2.7.11.1 KIAA0451DKFZp686L1738 MRCK alpha MRCK MRCKADKFZp686P1738 Myotonic dystrophy kinase-related CDC42-binding kinase alpha myotonic dystrophy kinase-related CDC42-binding protein kinase alpha Myotonic dystrophy protein kinase-like alpha PK428FLJ23347 serine/threonine-protein kinase MRCK alpha ser-thr protein kinase PK428 ser-thr protein kinase related to the myotonic dystrophy protein kinase

Research Areas for MRCK

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Protein Kinase