MMRN1 Products

Antibodies
MMRN1 Antibody
MMRN1 Antibody
NBP1-84014
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
MMRN1 Antibody (4B9)
MMRN1 Antibody (4B9)
H00022915-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
MMRN1 Antibody (1G10)
MMRN1 Antibody (1G10)
H00022915-M04
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
MMRN1 Overexpression Lysate ( ...
MMRN1 Overexpression Lysate (Native)
NBL1-13163
Applications: WB
Proteins
Recombinant Human MMRN1 Prote ...
Recombinant Human MMRN1 Protein
H00022915-Q01
Species: Hu
Applications: WB, ELISA, PA
MMRN1 Recombinant Protein Ant ...
MMRN1 Recombinant Protein Antigen
NBP1-84014PEP
Species: Hu
Applications: AC
RNAi
MMRN1 RNAi
MMRN1 RNAi
H00022915-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

MMRN1, also known as Multimerin-1, has 2 isoforms, a 1,228 amino acid long isoform that is 138 kDa and a short 531 amino acid isoform that is 58 kDa; synthesized by endothelial cells and megakaryocytes: stored in platelet alpha granules and endothelial cell Weibel-Palade bodies; can be found in vascular tissues such as placenta, lung, and liver. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers; it is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V and as an extracellular matrix or adhesive protein. Studies on this protein have shown a relationship with the following diseases and disorders: bleeding disorder, quebec platelet disorder, neonatal alloimmune thrombocytopenia, von Willebrand's disease, polycythemia vera, myocardial infarction, atrial fibrillation, thrombocytopenia, polycythemia, vascular disease, diabetic retinopathy, thrombosis, periodontitis, periodontal disease, hepatitis b, Parkinson's disease, vaginitis, asthma, and colorectal cancer. The MMRN1 protein has also shown an interaction with CDKN2A, F5, APC, A2M, ALB, and 30 other proteins in hemostasis, platelet degranulation, platelet activation, signaling and aggregation, and response to elevated platelet cytosolic Ca2+ pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 22915
Alternate Names
  • EMILIN-4
  • GPIA*
  • Endothelial cell multimerin
  • multimerin-1
  • Elastin microfibril interfacer 4
  • glycoprotein Ia*
  • Elastin microfibril interface located protein 4
  • EMILIN4GPIa*
  • ECMmultimerin
  • MMRN
  • multimerin 1

Pathways for MMRN1

View related products by pathway and learn more about each of the pathways below.

Coagulation
Platelet Activation
Cell Adhesion
Dna Repair
Endocytosis
Chromosome Segregation
Secretion

PTMs for MMRN1

Learn more about PTMs related to MMRN1.

Cleavage

Bioinformatics Tool for MMRN1

Discover related pathways, diseases and genes to MMRN1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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