MKP-3/DUSP6 Products

Antibodies
MKP-3/DUSP6 Antibody (3G2)
MKP-3/DUSP6 Antibody (3G2)
H00001848-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P, RNAi
Host: Mouse Monoclonal
MKP-3/DUSP6 Antibody (363246) ...
MKP-3/DUSP6 Antibody (363246)
MAB3576
Species: Hu, Mu, Rt
Applications: WB
Host: Mouse Monoclonal
MKP-3/DUSP6 Antibody
MKP-3/DUSP6 Antibody
NBP2-26174
Species: Hu, Mu, Rt, Po
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
MKP-3/DUSP6 Overexpression Ly ...
MKP-3/DUSP6 Overexpression Lysate ...
H00001848-T01
Species: Hu
Applications: WB
MKP-3/DUSP6 Overexpression Ly ...
MKP-3/DUSP6 Overexpression Lysate ...
NBL1-10057
Applications: WB
MKP-3/DUSP6 Overexpression Ly ...
MKP-3/DUSP6 Overexpression Lysate ...
NBL1-10058
Applications: WB
Proteins
Recombinant Human MKP-3/DUSP6 ...
Recombinant Human MKP-3/DUSP6 Protein
NBP2-51786
Species: Hu
Applications: PAGE
RNAi
MKP-3/DUSP6 RNAi
MKP-3/DUSP6 RNAi
H00001848-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
MKP-3/DUSP6 RNAi
MKP-3/DUSP6 RNAi
H00001848-R01
Species: Hu
Applications: RNAi, RNAi SP
MKP-3/DUSP6 RNAi
MKP-3/DUSP6 RNAi
H00001848-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

DUSP6 is encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 1848
Alternate Names
  • Mitogen-activated protein kinase phosphatase 3
  • EC 3.1.3.48
  • Dual specificity protein phosphatase PYST1
  • EC 3.1.3.16
  • MKP-3
  • MKP3serine/threonine specific protein phosphatase
  • PYST1dual specificity protein phosphatase 6
  • MAP kinase phosphatase 3
  • dual specificity phosphatase 6

Research Areas for MKP-3/DUSP6

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for MKP-3/DUSP6

Discover related pathways, diseases and genes to MKP-3/DUSP6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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