MEKK1 Products

Antibodies
MEKK1 Antibody
MEKK1 Antibody
NBP2-58101
Species: Hu, Mu, Rt
Applications: ICC/IF
Host: Rabbit Polyclonal
MEKK1 Antibody (2F6)
MEKK1 Antibody (2F6)
H00004214-M01
Species: Hu
Applications: WB, ELISA, PLA
Host: Mouse Monoclonal
Proteins
MEKK1 Recombinant Protein Ant ...
MEKK1 Recombinant Protein Antigen
NBP2-58101PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human MEKK1 Prote ...
Recombinant Human MEKK1 Protein
H00004214-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
MEKK1 RNAi
MEKK1 RNAi
H00004214-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

MEKKs (Mitogen activated protein kinase kinase kinases) are serine-threonine kinases that act as the first tier of cellular MAP kinase pathways by activation of MAP/ERK kinases, or MEKs. Many enzymes with MEKK activity have been identified, including MEKK1-4, Raf, MLK3, TAK, and DLK. MEKKs generally display little similarity outside of their catalytic kinase domains. MEKK1-4 are nearly 50% identical within their catalytic domains, and are known to regulate Erk, Jnk, and p38 MAP kinase pathways. MEKK2 and MEKK3 bind MEK5 via conserved PB1 domains, leading to downstream activation of Erk5.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Product By Gene ID 4214
Alternate Names
  • MAPK/ERK kinase kinase 1
  • MEKK1EC 2.7.11.25
  • MAPKKK1MAP/ERK kinase kinase 1
  • MEKKMEKK 1
  • MEK kinase 1
  • mitogen-activated protein kinase kinase kinase 1

Research Areas for MEKK1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Lipid and Metabolism
MAP Kinase Signaling
mTOR Pathway
Phospho-Specific
Protein Kinase
Signal Transduction
Tyrosine Kinases

Bioinformatics Tool for MEKK1

Discover related pathways, diseases and genes to MEKK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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