MCM7 Products

Antibodies
MCM7 Antibody (6C2)
MCM7 Antibody (6C2)
H00004176-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, PLA
Host: Mouse Monoclonal
MCM7 Antibody
MCM7 Antibody
Species: Hu
Applications: WB, PLA
Host: Goat Polyclonal
Antibody Pairs
MCM7 Antibody Pair
MCM7 Antibody Pair
H00004176-PW1
Species: Hu
Applications: WB, IP
Lysates
MCM7 Overexpression Lysate (N ...
MCM7 Overexpression Lysate (Native)
NBL1-12956
Applications: WB
MCM7 Overexpression Lysate (D ...
MCM7 Overexpression Lysate (Denatu...
H00004176-T01
Applications: WB
Proteins
MCM7 Recombinant Protein
MCM7 Recombinant Protein
NBP2-51540
Species: Hu
Applications: PAGE
MCM7 Recombinant Protein Anti ...
MCM7 Recombinant Protein Antigen
NBP1-85721PEP
Species: Hu
Applications: AC
RNAi
MCM7 RNAi
MCM7 RNAi
H00004176-R03
Species: Hu
MCM7 RNAi
MCM7 RNAi
H00004176-R04
Species: Hu

Description

The minichromosome maintenance (MCM7) helicase complex functions to initiate and elongate replication forks. Cell cycle checkpoint signaling pathways regulate DNA replication to maintain genomic stability (1). MCM7 is a putative human homologue of yeast CDC47 and a member of the MCM protein family, which has been implicated in the regulatory machinery causing DNA to replicate only once in the S phase. Findings indicate that MCM7 protein together with other MCM proteins participates in the regulation of mammalian DNA replication (2). In HeLa cells, depletion of MCM7 with small-interfering RNA suppressed ultraviolet (UV) light- or aphidicolin-induced hChk1 phosphorylation, and abolished UV-induced S-phase checkpoint activation. These results demonstrate that MCM7 plays a direct role in the transmission of DNA damage signals from active replication forks to the S-phase checkpoint machinery in human cells (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 4176
Alternate Names
  • EC 3.6.4.12
  • minichromosome maintenance deficient (S. cerevisiae) 7
  • minichromosome maintenance deficient 7
  • MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)
  • homolog of S. cerevisiae Cdc47
  • CDC47 homolog
  • DNA replication licensing factor MCM7
  • P1.1-MCM3
  • MCM2PNAS146
  • CDC47P85MCM
  • P1CDC47
  • minichromosome maintenance complex component 7

Research Areas for MCM7

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Cellular Markers
Core ESC-Like Genes
DNA Repair
Stem Cell Markers

PTMs for MCM7

Learn more about PTMs related to MCM7.

Phosphorylation
Cleavage
Acetylation
Ubiquitination
Dephosphorylation
Methylation

Bioinformatics Tool for MCM7

Discover related pathways, diseases and genes to MCM7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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