Mcl-1 Products

Antibodies
Mcl-1 Antibody
Mcl-1 Antibody
NB100-56146
Species: Hu
Applications: WB, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Mcl-1 Antibody (10F6)
Mcl-1 Antibody (10F6)
Species: Hu
Applications: WB, Flow, IHC, IHC-P, IF
Host: Mouse Monoclonal
Mcl-1 Antibody (542808) [Unco ...
Mcl-1 Antibody (542808) [Unconjuga...
MAB828
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Proteins
Mcl-1 Recombinant Protein
Mcl-1 Recombinant Protein
NBP2-51510
Species: Hu
Applications: PAGE
Mcl-1 Recombinant Protein Ant ...
Mcl-1 Recombinant Protein Antigen
NBP1-90006PEP
Species: Hu
Applications: AC
Mcl-1 Recombinant Protein Ant ...
Mcl-1 Recombinant Protein Antigen
NBP2-52968PEP
Species: Hu
Applications: AC
RNAi
Mcl-1 RNAi
Mcl-1 RNAi
H00004170-R01
Species: Hu
Mcl-1 RNAi
Mcl-1 RNAi
H00004170-R02
Species: Hu

Description

Mcl-1 (Myeloid cell leukemia-1) is Bcl-2-related and was identified as an early-induction gene that increased in expression during the differentiation of human myeloblastic leukemia cell ML-1, or exposure to different DNA damaging agents. The level of Mcl-1 is decreased in peripheral B lymphocytes undergoing apoptosis following treatment with apoptotic stimuli such as TGF-alpha 1 and forskolin. Expression of Mcl-1 is able to delay apoptosis induced by over-expression of c-myc in CHO 5AHSmyc cells. In hematopoietic FDC-P1 cells, Mcl-1 interacts with another Bcl-2-related protein, Bax, and prolongs cell viability after treatment with different apoptotic reagents.This monoclonal antibody detected a 37kd MCL1 in BCBL-1 cell lysate.

Bioinformatics

Entrez Human
Product By Gene ID 4170
Alternate Names
  • MCL1L
  • Bcl2-L-3
  • MCL1-ES
  • myeloid cell leukemia ES
  • EAT
  • induced myeloid leukemia cell differentiation protein Mcl-1
  • mcl1/EAT
  • bcl2-L-3
  • Bcl-2-related protein EAT/mcl1
  • TM
  • Bcl-2-like protein 3
  • MGC1839
  • Mcl-1
  • BCL2L3MGC104264
  • MCL1S
  • myeloid cell leukemia sequence 1 (BCL2-related)

Research Areas for Mcl-1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Signal Transduction
Tumor Suppressors

Bioinformatics Tool for Mcl-1

Discover related pathways, diseases and genes to Mcl-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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