Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: WB, Bioactivity
Species: Hu
Applications: Func, PAGE, Bioactivity
Species: Rt
Applications: Bioactivity
Description
MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of a specific mutation changing the previously numbered codon 50 from ATG to AGG, or deletion of that codon, has been reported in a variety of solid tumors. With the protein size correction, this codon is now identified as the initiation codon. [provided by RefSeq]
Bioinformatics
Product By Gene ID |
7873 |
Alternate Names |
- mesencephalic astrocyte-derived neurotrophic factor
- ARP
- arginine-rich, mutated in early stage tumors
- Protein ARMET
- Arginine-Rich Protein
- ARMET
|
Bioinformatics Tool for MANF
Discover related pathways, diseases and genes to MANF. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.