MafA Products

MafA Overexpression Lysate
MafA Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human MafA GST (N ...
Recombinant Human MafA GST (N-Term...
Species: Hu
Applications: WB, ELISA, PA, AP


Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only beta cell-specific activator. MafA selectively induces endogenous insulin transcription in non-beta cells. MafA was also first detected in the insulin-producing cells formed during the second and predominant phase of beta cell differentiation, and absent in the few insulin-positive cells found in Nkx6.1(-/-) pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MafA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.


Entrez Mouse
Uniprot Mouse
Product By Gene ID 389692
Alternate Names
  • hMafA
  • Pancreatic beta-cell-specific transcriptional activator
  • RIPE3b1
  • RIPE3B1
  • transcription factor MafA
  • Transcription factor RIPE3b1
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
  • V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

Research Areas for MafA

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Lipid and Metabolism
Transcription Factors and Regulators

Bioinformatics Tool for MafA

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