LOXL4 Products

Description

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	84171
Alternate Names	EC 1.4.3 EC 1.4.3.- FLJ21889 LOX L4 LOXC LOXClysyl oxidase related C LOXL4 lysyl oxidase homolog 4 lysyl oxidase-like 4 Lysyl oxidase-like protein 4 Lysyl oxidase-related protein C

Research Areas for LOXL4

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Lipid and Metabolism