Lipase A Products

Mouse Lipase A ELISA Kit (Col ...
Mouse Lipase A ELISA Kit (Colorime...
Species: Mu
Applications: ELISA
Lipase A Overexpression Lysat ...
Lipase A Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human Lipase A GS ...
Recombinant Human Lipase A GST (N-...
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Lipase A Recombinant Protein ...
Lipase A Recombinant Protein Antigen
Species: Hu
Applications: AC


Lipase A, also known as LIPA or Lysosomal acid lipase/cholesteryl ester hydrolase, has a 399 amino acid long isoform that is 45 kDa and a short 343 amino acid isoform that is 39 kDa; lysosome located; is very important for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles, and also in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. This protein is currently being studied for involvement in the following diseases and disorders: cholesteryl ester storage disease, wolman disease, cholesterol, cholesterol ester storage disease, lysosomal storage disease, coronary heart disease, hepatitis c, splenomegaly, hepatitis b, hepatitis, hyperlipidemia, hypercholesterolemia, tuberculosis, obesity atherosclerosis, alzheimer's disease, neisseria meningitides, lipid storage disease, lipodystrophy, pandas, wolman disease, and blepharitis. The LIPA protein has been shown to interact with HIST1H4A, HIST1H4B, HIST1H4C, SOAT1, and HIST1H4E in cholesterol and sphingolipids transport / distribution to the intracellular membrane compartments (normal and CF), steroid biosynthesis, and lysosome pathways.


Entrez Human
Uniprot Human
Product By Gene ID 3988
Alternate Names
  • EC 3.1.1
  • EC
  • Lipase A
  • Sterol esterase
  • lysosomal acid lipase/cholesteryl ester hydrolase
  • Cholesteryl esterase
  • lysosomal acid lipase
  • Acid cholesteryl ester hydrolase
  • LALCESDcholesterol ester hydrolase
  • lipase A, lysosomal acid, cholesterol esterase

Research Areas for Lipase A

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Lipid and Metabolism

PTMs for Lipase A

Learn more about PTMs related to Lipase A.


Bioinformatics Tool for Lipase A

Discover related pathways, diseases and genes to Lipase A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related Lipase A Blog Posts

Check out the latest blog posts on Lipase A.
How do Lipase A and the CD36 Antibody Relate to Each Other
Obesity, diabetes and metabolic disorders are dramatically on the increase, linked to disorders such as heart disease, stroke and cancer. To combat this, research groups are studying metabolism at both a cellular and a systemic level. Although we at N...    Read more.
Read more Lipase A related blogs.