Lipase A Products

Antibodies
Lipase A Antibody
Lipase A Antibody
NBP1-54155
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lipase A Antibody
Lipase A Antibody
NBP2-47397
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lipase A Antibody
Lipase A Antibody
H00003988-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Antibody Pairs
Lipase A Antibody Pair
Lipase A Antibody Pair
H00003988-PW1
Species: Hu
Applications: WB, IP
Kits
Lipase A Assay Kit
Lipase A Assay Kit
KA0877
Species: Ma
Applications: Func
Lipase A Assay Kit
Lipase A Assay Kit
KA1654
Applications: Func
Lysates
Lipase A Overexpression Lysat ...
Lipase A Overexpression Lysate (De...
H00003988-T01
Species: Hu
Applications: WB
Lipase A Overexpression Lysat ...
Lipase A Overexpression Lysate (Na...
NBL1-12546
Applications: WB
Proteins
Lipase A Recombinant Protein
Lipase A Recombinant Protein
H00003988-P01
Species: Hu
Applications: WB, ELISA, PA
Lipase A Recombinant Protein ...
Lipase A Recombinant Protein Antigen
NBP2-47397PEP
Species: Hu
Applications: AC
RNAi
Lipase A RNAi
Lipase A RNAi
H00003988-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Lipase A, also known as LIPA or Lysosomal acid lipase/cholesteryl ester hydrolase, has a 399 amino acid long isoform that is 45 kDa and a short 343 amino acid isoform that is 39 kDa; lysosome located; is very important for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles, and also in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. This protein is currently being studied for involvement in the following diseases and disorders: cholesteryl ester storage disease, wolman disease, cholesterol, cholesterol ester storage disease, lysosomal storage disease, coronary heart disease, hepatitis c, splenomegaly, hepatitis b, hepatitis, hyperlipidemia, hypercholesterolemia, tuberculosis, obesity atherosclerosis, alzheimer's disease, neisseria meningitides, lipid storage disease, lipodystrophy, pandas, wolman disease, and blepharitis. The LIPA protein has been shown to interact with HIST1H4A, HIST1H4B, HIST1H4C, SOAT1, and HIST1H4E in cholesterol and sphingolipids transport / distribution to the intracellular membrane compartments (normal and CF), steroid biosynthesis, and lysosome pathways.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 3988
Alternate Names
  • EC 3.1.1
  • EC 3.1.1.13
  • Lipase A
  • Sterol esterase
  • lysosomal acid lipase/cholesteryl ester hydrolase
  • Cholesteryl esterase
  • lysosomal acid lipase
  • Acid cholesteryl ester hydrolase
  • LALCESDcholesterol ester hydrolase
  • lipase A, lysosomal acid, cholesterol esterase

Research Areas for Lipase A

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

PTMs for Lipase A

Learn more about PTMs related to Lipase A.

Cleavage
Phosphorylation
Decarboxylation

Bioinformatics Tool for Lipase A

Discover related pathways, diseases and genes to Lipase A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Lipase A Blog Posts

Check out the latest blog posts on Lipase A.
How do Lipase A and the CD36 Antibody Relate to Each Other
Obesity, diabetes and metabolic disorders are dramatically on the increase, linked to disorders such as heart disease, stroke and cancer. To combat this, research groups are studying metabolism at both a cellular and a systemic level. Although we at N...    Read more.
Read more Lipase A related blogs.