Laminin S/Laminin beta 2 Products

Description

The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated alpha, beta and gamma. A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues. During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells. The beta-2 laminin chain plays a role in melanoma spread, promoting tumor migration along the abluminal surface of vessel, a phenomenon which has been termed extra-vascular migratory metastasis.

Bioinformatics

Entrez	3913 Human 25473 Rat
Uniprot	P55268 Human NP_002283 Human
Product By Gene ID	3913
Alternate Names	Laminin-4 subunit beta laminin subunit beta-2 Laminin-3 subunit beta laminin S Laminin-15 subunit beta Laminin-14 subunit beta S-laminin subunit beta Laminin-11 subunit beta S-LAM beta Laminin B1s chain LAMSLaminin-9 subunit beta Laminin-7 subunit beta laminin, beta 2 (laminin S)

Diseases related to Laminin S/Laminin beta 2

Discover more about diseases related to Laminin S/Laminin beta 2.

Nephrotic Syndrome
Microcoria And Congenital Nephrotic Syndrome
Congenital Nephrotic Syndrome
Eye Abnormalities
Kidney Diseases
Proteinuria Of Undiagnosed Cause
Kidney Failure
Sclerosis
Diffuse Mesangial Sclerosis (disorder)
Kidney Failure, Chronic
Glioblastoma
Nephrosis
Retinal Detachment
Tissue Adhesions
Blind Vision
Pupil Disorders
Myasthenic Syndromes, Congenital
Segmental Glomerulosclerosis
Malignant Neoplasms
Neoplasms

Pathways for Laminin S/Laminin beta 2

View related products by pathway and learn more about each of the pathways below.

Localization
Glomerular Filtration
Cell Adhesion
Pathogenesis
Cell Migration
Translation
Secretion
Cell Proliferation
Immune Response
Metaphase
Floral Organ Development
Methylation
Organ Development
Cell Motility
Eye Development

PTMs for Laminin S/Laminin beta 2

Learn more about PTMs related to Laminin S/Laminin beta 2.

Cleavage
Methylation

Bioinformatics Tool for Laminin S/Laminin beta 2

Discover related pathways, diseases and genes to Laminin S/Laminin beta 2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.