Lambda Light Chain Products

Antibodies
Lambda Light Chain Antibody
Lambda Light Chain Antibody
NB100-62139
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC-Fr, IHC-P, IP, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Secondary Antibodies
Goat anti-Human Lambda Light ...
Goat anti-Human Lambda Light Chain...
NB7471
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Goat anti-Mouse Lambda Light ...
Goat anti-Mouse Lambda Light Chain...
NB7552
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Goat Polyclonal
Goat anti-Human Lambda Light ...
Goat anti-Human Lambda Light Chain...
NBP1-73715
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Goat Polyclonal

Description

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30, the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins). This antibody stains only lambda light chain containing cells in human lymphoid tissues.

Bioinformatics

Entrez Human
Human
Uniprot Human
Product By Gene ID 3536
Alternate Names
  • IGLC
  • immunoglobulin lambda constant group

Research Areas for Lambda Light Chain

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology

Bioinformatics Tool for Lambda Light Chain

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