WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IPHost:
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Mouse Monoclonal
WB, ELISA, FLISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IPHost:
WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-PHost:
WB, ELISA, ICC/IF, IHC, IHC-PHost:
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Sheep Polyclonal
All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30, the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins). This antibody stains only lambda light chain containing cells in human lymphoid tissues.
|Product By Gene ID
- immunoglobulin lambda constant group
Research Areas for Lambda Light Chain
Find related products by research area and learn more about each of the different research areas below.Adaptive ImmunityImmunology
Bioinformatics Tool for Lambda Light Chain
Discover related pathways, diseases and genes to Lambda Light Chain. Need help? Read the Bioinformatics Tool Guide
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