Lactate Dehydrogenase B Products

Description

Lactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), because it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. All LDH subunits can combine to form various terameric isoenzymes (140 kDa). Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor (2).

Bioinformatics

Product By Gene ID	3945
Alternate Names	EC 1.1.1 EC 1.1.1.27 Epididymis Secretory Protein Li 281 HEL-S-281 Lactate Dehydrogenase B LDH heart subunit LDHB LDH-B LDHBD LDH-H L-lactate dehydrogenase B chain Renal Carcinoma Antigen NY-REN-46 TRG-5

Research Areas for Lactate Dehydrogenase B

Find related products by research area and learn more about each of the different research areas below.

HIF Target Genes
Hypoxia
Mitochondrial-Mediated Pathway