Kir6.1 Products

Antibodies
Kir6.1 Antibody
Kir6.1 Antibody
NBP1-87710
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Kir6.1 Antibody
Kir6.1 Antibody
NBP2-85158
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
Kir6.1 Overexpression Lysate
Kir6.1 Overexpression Lysate
NBL1-12174
Species: Hu
Applications: WB
Proteins
Kir6.1 Recombinant Protein An ...
Kir6.1 Recombinant Protein Antigen
NBP1-87710PEP
Species: Hu
Applications: AC

Description

The Kir6.1 (KCNJ8) gene is essential in membrane function as it encodes an inward-rectifier potassium channel protein that is 424 amino acids long and has a mass of nearly 48 kDA. Dysfunctions in the Kir6.1 gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). Research is investigating its role in various diseases such as retinitis, hypoxia, pancreatitis, myocardial infarction, spasticity, leiomyoma, acute myocardial infarction, and prinzmetal angina. The Kir6.1 gene plays a significant role in ATP sensitive potassium channels, SIDS susceptibility pathways, dopamine feedback into cAMP pathway, and the CFTR-dependent regulation of ion channels in airway epithelium. It interacts with other genes such as KCNJ2, ABCC8, ABCC9, and KCNJ11.

Bioinformatics

Entrez Mouse
Rat
Human
Uniprot Human
Human
Alternate Names
  • ATP-sensitive inward rectifier potassium channel 8
  • Inward rectifier K(+) channel Kir6.1
  • inwardly rectifying potassium channel KIR6.1
  • Kir6.1
  • KIR6.1
  • Potassium channel, inwardly rectifying subfamily J member 8
  • potassium inwardly-rectifying channel, subfamily J, member 8
  • uKATP-1