Kallikrein 8/Neuropsin Products

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer.

Bioinformatics

Entrez	11202 Human
Uniprot	NM_007196 Human NP_009127 Human NP_009127.1 Human O60259 Human
Product By Gene ID	11202
Alternate Names	EC 3.4.21 EC 3.4.21.118 hK8 HNP kallikrein 8 (neuropsin/ovasin) kallikrein-related peptidase 8 KLK8 protein type 1 KLK8 protein type 2 KLK8 neuropsin type 1 neuropsin type 2 Neuropsin NP NRPN Ovasin ovasin PRSS19kallikrein-8 Serine protease 19 Serine protease TADG-14 TADG14neuropsin Tumor-associated differentially expressed gene 14 protein

Diseases related to Kallikrein 8/Neuropsin

Discover more about diseases related to Kallikrein 8/Neuropsin.

Malignant Neoplasms
Nervousness
Neoplasms
Carcinoma
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Malignant Neoplasm Of Breast
Dermatologic Disorders
Cell Invasion
Kindling, Neurologic
Malignant Squamous Cell Neoplasm
Adenocarcinoma
Tissue Adhesions
Psoriasis
Epilepsy
Dermatitis
Malignant Neoplasm Of Lung
Hyperkeratosis
Inflammation
Dermatitis, Atopic

Pathways for Kallikrein 8/Neuropsin

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Pathogenesis
Localization
Secretion
Cell Adhesion
Proteolysis
Keratinocyte Differentiation
Cell Proliferation
Cell Death
Keratinocyte Proliferation
Tissue Development
Cell Differentiation
Transport
Keratinization
Long-term Synaptic Potentiation
Cell Migration
Brain Development
Aging
Reverse Transcription
Chemotaxis
Cell Motility

Research Areas for Kallikrein 8/Neuropsin

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Neuroscience

PTMs for Kallikrein 8/Neuropsin

Learn more about PTMs related to Kallikrein 8/Neuropsin.

Cleavage
Glycosylation
Amination
Methylation

Bioinformatics Tool for Kallikrein 8/Neuropsin

Discover related pathways, diseases and genes to Kallikrein 8/Neuropsin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.