Kallikrein 6/Neurosin Products

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion. It is upregulated in several types of cancers including colon and ovarian cancers.

Bioinformatics

Entrez	5653 Human
Uniprot	NM_001012964 Human NM_002774 Human Q92876 Human AAH15525 Human NP_002765 Human NP_002765.1 Human
Product By Gene ID	5653
Alternate Names	kallikrein 6 (neurosin, zyme) EC 3.4.21 SP59 ZYME PRSS18 Zyme Serine protease 9 Neurosin Serine protease 18 EC 3.4.21.- Protease M zyme neurosin kallikrein-6 Klk7 hK6 Bssp PRSS9MGC9355 protease, serine, 18 kallikrein-related peptidase 6

Diseases related to Kallikrein 6/Neurosin

Discover more about diseases related to Kallikrein 6/Neurosin.

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Carcinoma
Nervousness
Malignant Paraganglionic Neoplasm
Alzheimer's Disease
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Cell Invasion
Mammary Neoplasms
Neoplasm Invasiveness
Epithelial Ovarian Cancer
Adenocarcinoma
Neurodegenerative Disorders
Colonic Neoplasms
Colorectal Cancer
Parkinson Disease
Malignant Tumor Of Colon

Pathways for Kallikrein 6/Neurosin

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Pathogenesis
Localization
Secretion
Cell Migration
Cell Proliferation
Dna Methylation
Methylation
Angiogenesis
Proteolysis
Cell Death
Keratinocyte Proliferation
Cell Growth
Gene Silencing
Cell Motility
Cell Communication
Glycosylation
Transport
Cell Adhesion
Cell Activation
Response To Camptothecin

Research Areas for Kallikrein 6/Neurosin

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Cancer
Cell Biology
Cellular Markers
Cytoskeleton Markers
Endothelial Cell Markers
Extracellular Matrix
Neurodegeneration
Neuroscience
Signal Transduction

PTMs for Kallikrein 6/Neurosin

Learn more about PTMs related to Kallikrein 6/Neurosin.

Cleavage
Methylation
Phosphorylation
Demethylation
Glycosylation
Deacetylation

Bioinformatics Tool for Kallikrein 6/Neurosin

Discover related pathways, diseases and genes to Kallikrein 6/Neurosin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.