JNK1/2/3 Products

Antibodies
JNK1/2/3 Antibody
JNK1/2/3 Antibody
NBP1-19872
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
JNK1/2/3 [p Thr178] Antibody
JNK1/2/3 [p Thr178] Antibody
NB100-92175
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IP
Host: Rabbit Polyclonal
Kits
JNK1/2/3 Assay Kit
JNK1/2/3 Assay Kit
KA0888
Species: Ma
Applications: WB, Func, IP
JNK1/2/3 Assay Kit
JNK1/2/3 Assay Kit
KA0889
Species: Ma
Applications: WB, Func, IP

Description

JNKs (c-Jun N-terminal kinases) belong to a family of MAP kinases that are involved in a variety of cellular processes, including transcriptional regulation and cellular proliferation, differentiation and development. JNK2 (c-Jun Nterminal kinase 2) and JNK3 (c-Jun N-terminal kinase 3) are 424 and 464 amino acid proteins, respectively, that each contain one protein kinase domain and use magnesium as a cofactor to catalyze the phosphorylation of target proteins, thereby playing a role in a variety of events throughout the cell. Both JNK2 and JNK3 exist as multiple alternatively spliced isoforms and are subject to post-translational phosphorylation on Thr 183 and Thr 221, respectively, an event which activates JNK2/JNK3 enzymatic activity. Defects in the gene encoding JNK3 are a cause of epileptic encephalopathy of the Lennox-Gastaut type, a group of epileptic disorders characterized by severe psychomotor delay and seizures.

Bioinformatics

Entrez Human
Human
Rat
Uniprot Human
Product By Gene ID 5599
Alternate Names
  • EC 2.7.11
  • MAPK 8
  • protein kinase JNK1
  • MAP kinase 8
  • mitogen-activated protein kinase 8 isoform JNK1 beta2
  • c-Jun N-terminal kinase 1
  • mitogen-activated protein kinase 8 isoform JNK1 alpha1
  • JNK-46
  • JUN N-terminal kinase
  • Stress-activated protein kinase JNK1
  • JNK1 beta protein kinase
  • Stress-activated protein kinase 1
  • JNK1 alpha protein kinase
  • PRKM8JNK
  • SAPK1JNK21B1/2
  • JNK1JNK1A2
  • EC 2.7.11.24
  • mitogen-activated protein kinase 8

Research Areas for JNK1/2/3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Breast Cancer
Cancer
Cell Cycle and Replication
Diabetes Research
Hypoxia
MAP Kinase Signaling
Phospho-Specific
Protein Kinase
Signal Transduction
Wnt Signaling Pathway

PTMs for JNK1/2/3

Learn more about PTMs related to JNK1/2/3.

Phosphorylation
Acetylation
Demethylation
Methylation

Bioinformatics Tool for JNK1/2/3

Discover related pathways, diseases and genes to JNK1/2/3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.