ITK Products

Antibodies
ITK Antibody (5G6)
ITK Antibody (5G6)
NBP2-37578
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
Host: Mouse Monoclonal
ITK Antibody
ITK Antibody
NB100-807
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
ITK Antibody
ITK Antibody
NBP1-30997
Species: Hu, Primate
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Antibody Pairs
ITK Antibody Pair
ITK Antibody Pair
H00003702-PW1
Species: Hu
Applications: WB, IP
Lysates
ITK Overexpression Lysate (Na ...
ITK Overexpression Lysate (Native)
NBL1-12080
Applications: WB
ITK Overexpression Lysate (De ...
ITK Overexpression Lysate (Denatured)
H00003702-T01
Species: Hu
Applications: WB
Proteins
ITK Recombinant Protein
ITK Recombinant Protein
H00003702-P01
Species: Hu
Applications: WB, ELISA, PA
ITK Partial Recombinant Prote ...
ITK Partial Recombinant Protein
H00003702-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ITK RNAi
ITK RNAi
H00003702-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Emtk/Itk/Tsk is a member of the Tec family of Protein Tyrosine Kinase (PTK) expressed in T, NK, and mast cells (1). Structurally, Emtk/Itk/Tsk possesses a tyrosine kinase (TK), a pleckstrin homology (PH) and a TEC homology domain. It also contains both SRC homology 2 (SH2) and a SRC homology 3 (SH3) domains (2). It lacks as well the amino-terminal myristylation signal and the negative autoregulatory phosphorylation site present in all members of the Src family of PTKs (3). Additionally, the Src tyrosine kinase LCK is required for Emtk/Itk/Tsk activation and recruitment by CD28 (4).

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3702
Alternate Names
  • T-cell-specific kinase
  • EC 2.7.10
  • Tyrosine-protein kinase Lyk
  • tyrosine-protein kinase ITK/TSK
  • Kinase EMT
  • homolog of mouse T-cell itk/tsk
  • PSCTK2
  • LYKMGC126258
  • EMTMGC126257
  • EC 2.7.10.2
  • IL2-inducible T-cell kinase

Research Areas for ITK

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

Bioinformatics Tool for ITK

Discover related pathways, diseases and genes to ITK. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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