INSL3 Products

Antibodies
INSL3 Antibody
INSL3 Antibody
NBP1-81223
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
INSL3 Overexpression Lysate ( ...
INSL3 Overexpression Lysate (Native)
NBL1-12005
Applications: WB
Proteins
Recombinant Human INSL3 Prote ...
Recombinant Human INSL3 Protein, CF
4544-NS
Species: Hu
Applications: BA
INSL3 Recombinant Protein Ant ...
INSL3 Recombinant Protein Antigen
NBP1-81223PEP
Species: Hu
Applications: AC

Description

Insulin-like 3 (INSL3), a member of the insulin-like hormone superfamily, is specifically expressed in Leydig cells of the fetal and postnatal testis and in theca cells of the postnatal ovary. It is synthesized as a 131-amino acid preproprotein, which contains a 24-amino acid signal peptide. The human INSL3 gene is assigned to bands p13.2-p12 of the short arm of chromosome 19 with the similar organization to that of insulin and relaxin. INSL3 induces gubernaculum development in an androgen-independent way, while androgen-mediated regression of the CSL occurs independently from Insl3. Moreover, INSL3 is a ligand for LGR8 and INSL3-LGR8 mutations are believed to be associated with human cryptorchidism.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Product By Gene ID 3640
Alternate Names
  • RLNL
  • Ley-I-L
  • Leydig insulin-like peptide
  • relaxin-like factor b
  • Relaxin-like factor
  • leydig insulin -like peptide
  • MGC119819
  • leydig insulin -like hormone
  • MGC119818
  • RLFley-I-L
  • insulin-like 3
  • insulin-like 3 (Leydig cell)

PTMs for INSL3

Learn more about PTMs related to INSL3.

Cleavage
Phosphorylation
Acetylation
Methylation

Bioinformatics Tool for INSL3

Discover related pathways, diseases and genes to INSL3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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