Importin-13 Products

Antibodies
Importin-13 Antibody
Importin-13 Antibody
NBP1-31508
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Importin-13 Antibody
Importin-13 Antibody
NBP2-14994
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Importin-13 Overexpression Ly ...
Importin-13 Overexpression Lysate ...
NBL1-12015
Applications: WB
Proteins
Importin-13 Recombinant Prote ...
Importin-13 Recombinant Protein
H00009670-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Importin-13 RNAi
Importin-13 RNAi
H00009670-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Importin-13 functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13. Expressed in fetal brain, heart, intestine and kidney. Belongs to the importin beta family. Contains 14 HEAT repeats. Contains 1 importin N-terminal domain.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 9670
Alternate Names
  • RanBP13
  • importin-13
  • Karyopherin-13
  • LGL2
  • Kap13
  • KAP13
  • Imp13
  • Ran-binding protein 13
  • Ran binding protein 13
  • IMP13
  • RANBP13late gestation lung 2
  • KIAA0724karyopherin-13
  • karyopherin 13
  • importin 13

Pathways for Importin-13

View related products by pathway and learn more about each of the pathways below.

Transport
Localization
Nuclear Import
Pathogenesis
Nuclear Transport
Cell Division
Mitosis
Cell Differentiation
Pachytene
Meiosis
Secretion

Research Areas for Importin-13

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism

Bioinformatics Tool for Importin-13

Discover related pathways, diseases and genes to Importin-13. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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