Importin-13 Products

Antibodies
Importin-13 Antibody - BSA Fr ...
Importin-13 Antibody - BSA Free
NBP1-31508
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Importin-13 Antibody - Azide ...
Importin-13 Antibody - Azide Free
NBP2-14994
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Lysates
Importin-13 Overexpression Ly ...
Importin-13 Overexpression Lysate
NBL1-12015
Species: Hu
Applications: WB
Proteins
Recombinant Human Importin-13 ...
Recombinant Human Importin-13 GST ...
H00009670-P01
Species: Hu
Applications: WB, ELISA, MA, AP

Description

Importin-13 functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBC9, the RBM8A/MAGOH complex, PAX6 and probably other members of the paired homeobox family. Also mediates nuclear export of eIF-1A, and the cytoplasmic release of eIF-1A is triggered by the loading of import substrates onto IPO13. Expressed in fetal brain, heart, intestine and kidney. Belongs to the importin beta family. Contains 14 HEAT repeats. Contains 1 importin N-terminal domain.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 9670
Alternate Names
  • Imp13
  • IMP13
  • importin 13
  • importin-13
  • Kap13
  • KAP13
  • karyopherin 13
  • Karyopherin-13
  • KIAA0724karyopherin-13
  • LGL2
  • Ran binding protein 13
  • Ran-binding protein 13
  • RanBP13
  • RANBP13late gestation lung 2

Research Areas for Importin-13

Find related products by research area and learn more about each of the different research areas below.

Lipid and Metabolism