IL-12 R beta 1 Products

Antibodies
Antibody Pairs
IL-12 R beta 1 Antibody Pair
IL-12 R beta 1 Antibody Pair
H00003594-PW1
Species: Hu
Applications: WB, IP
Lysates
IL-12 R beta 1 Overexpression ...
IL-12 R beta 1 Overexpression Lysa...
H00003594-T01
Species: Hu
Applications: WB
IL-12 R beta 1 Overexpression ...
IL-12 R beta 1 Overexpression Lysa...
NBP2-07735
Applications: WB
IL-12 R beta 1 Overexpression ...
IL-12 R beta 1 Overexpression Lysa...
NBL1-11902
Applications: WB
Proteins
IL-12 R beta 1 Recombinant Pr ...
IL-12 R beta 1 Recombinant Protein
NBP2-52085
Species: Hu
Applications: PAGE
IL-12 R beta 1 Recombinant Pr ...
IL-12 R beta 1 Recombinant Protein
NBP2-51952
Species: Hu
Applications: PAGE
RNAi
IL-12 R beta 1 RNAi
IL-12 R beta 1 RNAi
H00003594-R03
Species: Hu
IL-12 R beta 1 RNAi
IL-12 R beta 1 RNAi
H00003594-R04
Species: Hu

Description

IL12RB1, also known as Interleukin-12 receptor subunit beta-1, has 3 isoforms, an isoform 1 that is 662 amino acid and 73 kDa, an isoform 2 that is 660 amino acid and 73 kDa, and an isoform3 that is 381 amino acid and 42 kDa; acts as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction; forms a functional, high affinity receptor for IL12 when combined with IL12RB2, and associates also with IL23R to form the interleukin-23 receptor which plays a role in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade. Current research is being pursued on this protein involvement in several diseases and disorders including immunodeficiency, mycobacterial and salmonella infections, salmonella gastroenteritis, mycobacterium infectious disease, myocarditis, lupus erythematosus, tuberculosis, sarcoidosis, neurological disorder, rheumatoid arthritis, gastroenteritis, asthma, and dermatitis. IL12RB1 protein involvement has been observed with relation to IL23R, IL23A, IL12A, IL12B, and IL12RB2 in the immune response IL-12 signaling pathway, immune response IL-22 signaling pathway, immune response IL-12-induced IFN-gamma production, cytokine production by Th17 cells in CF, and Jak-STAT signaling pathway.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 3594
Alternate Names
  • CD212 antigen
  • IL-12 receptor subunit beta-1
  • IL12R
  • IL-12 receptor beta component
  • interleukin-12 receptor subunit beta-1
  • IL12RB
  • interleukin-12 receptor beta-1 chain
  • IL-12RB1
  • MGC34454
  • IL-12R-beta-1
  • IL-12R-BETA1
  • CD212
  • IL-12R subunit beta-1
  • interleukin 12 receptor, beta 1

Research Areas for IL-12 R beta 1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for IL-12 R beta 1

Learn more about PTMs related to IL-12 R beta 1.

Phosphorylation
Cleavage
Acetylation

Bioinformatics Tool for IL-12 R beta 1

Discover related pathways, diseases and genes to IL-12 R beta 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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