IL-10 R beta Products

Description

IL10RB, also known as Interleukin-10 receptor subunit beta, is a 325 amino acid protein that is 37 kDa; belongs to the type II cytokine receptor family; cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29; and its co-expression with IL10RA proteins is needed for IL10-induced signal transduction. This protein is currently being studied for research on several diseases and disorders including inflammatory bowel disease 25, early onset, autosomal recessive, hepatitis b virus, inflammatory bowel disease, hepatitis b, interferon, respiratory syncytial virus bronchiolitis, graft versus host disease, ulcerative colitis crohn's disease, anaplastic large cell lymphoma, secondary hyperparathyroidism, mumps, systemic lupus erythematosus, measles, bronchiolitis, rubella, cblc, lupus erythematosus, rheumatoid arthritis, colitis, and tumors. Interactions with IL10RB have been shown to involve IL22, UCN3, IL10RA, IL28A, and IL10 in cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, toxoplasmosis, tuberculosis, antioxidant action of vitamin-C, immune response IL-22 signaling pathway, and molecular mechanisms of cancer pathway.

Bioinformatics

Entrez	3588 Human
Uniprot	AAH01903 Human AAH01903.1 Human NP_000619.3 Human Q08334 Human
Product By Gene ID	3588
Alternate Names	CDw210b antigen CRF2-4IL-10R subunit 2 CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B D21S58 D21S66 IBD25 IL-10 receptor subunit beta IL-10R2IL-10R subunit beta IL-10RB interleukin 10 receptor, beta Interleukin-10 receptor subunit 2 interleukin-10 receptor subunit beta member 4

Research Areas for IL-10 R beta

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity