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804-GB) was serially diluted and captured by Mouse Anti-Human IGFBP‑4 Monoclonal Antibody (Catalog # MAB8041) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human IGFBP‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF804) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
804-GB) inhibits Recombinant Human IGF-II (Catalog # 292-G2) induced proliferation in the MCF-7 human breast cancer cell line in a dose-dependent manner (orange line). Inhibition of Recombinant Human IGF-II (14 ng/mL) activity elicited by Recombinant Human IGFBP-4 (0.3 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human IGFBP-4 Monoclonal Antibody (Catalog # MAB8041). The ND50 is typically 20-80 µg/mL." class="big_lightbox" target="_blank">
804-GB) was serially diluted and captured by Mouse Anti-Human IGFBP‑4 Monoclonal Antibody (Catalog # MAB8041) coated on a Clear Polystyrene Microplate (Catalog # DY990). Goat Anti-Human IGFBP‑4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF804) was biotinylated and incubated with the protein captured on the plate. Detection of the standard curve was achieved by incubating Streptavidin-HRP (Catalog # DY998)" class="big_lightbox" target="_blank">
IGFBP4 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq]
![Neutralization IGFBP-4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af804_human-igfbp-4-affinity-purified-polyclonal-ab-neutralization-21112025151421.jpg)
![Neutralization IGFBP-4 Antibody (82314) [Unconjugated]](http://images.novusbio.com/images/antibody/IGFBP-4_MAB8041_Block_Neutralize_9282.jpg)
![N/A IGFBP-4 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_IGFBP4_DY804_ELISA_2237.jpg)
![Immunohistochemistry IGFBP-4 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/IGFBP-4_AF804_Immunohistochemistry_6899.jpg)
![Immunohistochemistry IGFBP-4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af804_human-igfbp-4-affinity-purified-polyclonal-ab-8220249505981.jpg)
![Immunohistochemistry IGFBP-4 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af804_human-igfbp-4-affinity-purified-polyclonal-ab-44202415425027.jpg)
![ELISA IGFBP-4 Antibody [Unconjugated]](http://images.novusbio.com/images/af804_human-igfbp-4-affinity-purified-polyclonal-ab-elisa-639201852916764191.jpg)
![ELISA IGFBP-4 Antibody (82314) [Unconjugated]](http://images.novusbio.com/images/mab8041_human-igfbp-4-mab-clone-82314-elisa-639201781287397201.jpg)
