IFN-gamma R1/CD119 Products

Antibodies
IFN-gamma R1/CD119 Antibody ( ...
IFN-gamma R1/CD119 Antibody (92101...
MAB6731
Species: Hu
Applications: WB, Flow, Neut
Host: Mouse Monoclonal
IFN-gamma R1/CD119 Antibody [ ...
IFN-gamma R1/CD119 Antibody [Uncon...
AF673
Species: Hu
Applications: WB, ICC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
IFN-gamma R1/CD119 Antibody ( ...
IFN-gamma R1/CD119 Antibody (GIR208)
MAB6732
Species: Hu
Applications: Neut
Host: Mouse Monoclonal
Antibody Pairs
IFN-gamma R1/CD119 Antibody P ...
IFN-gamma R1/CD119 Antibody Pair
H00003459-PW1
Species: Hu
Applications: WB, IP
Lysates
IFN-gamma R1/CD119 Overexpres ...
IFN-gamma R1/CD119 Overexpression ...
H00003459-T01
Species: Hu
Applications: WB
IFN-gamma R1/CD119 Overexpres ...
IFN-gamma R1/CD119 Overexpression ...
NBL1-11852
Applications: WB
Proteins
IFN-gamma R1/CD119 Recombinan ...
IFN-gamma R1/CD119 Recombinant Pro...
NBP2-49406PEP
Species: Hu
Applications: AC
IFN-gamma R1/CD119 Recombinan ...
IFN-gamma R1/CD119 Recombinant Pro...
NBP1-94206
Species: Mu
IFN-gamma R1/CD119 Recombinan ...
IFN-gamma R1/CD119 Recombinant Pro...
H00003459-G01
Species: Hu
RNAi
IFN-gamma R1/CD119 RNAi
IFN-gamma R1/CD119 RNAi
H00003459-R02
Species: Hu

Description

IFN gamma receptor beta is part of the receptor for interferon gamma. This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The extracellular portion of both the IFN gamma receptor alpha and beta chains must be species matched. The IFN gamma receptor beta chain is expressed on T and B cells, NK cells, monocytes/ macrophages, and fibroblasts. Binding of IFN gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. It is also likely to interact with GAF. IFN gamma initiates and regulates a variety of immune responses and is required for signal transduction. Contains 2 fibronectin type III domains. Defects in IFN gamma Receptor beta are a cause of mendelian susceptibility to mycobacterial disease (MSMD), a rare condition that confers predisposition to illness caused by several mycobacteria strains.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 3459
Alternate Names
  • FLJ45734
  • interferon-gamma receptor alpha chain
  • IFN-gamma receptor 1
  • immune interferon receptor 1
  • CD119 antigen
  • AVP, type 2
  • IFN-gamma-R1
  • type 2
  • CD119
  • IFNGR
  • interferon gamma receptor 1

Research Areas for IFN-gamma R1/CD119

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Neuroscience

PTMs for IFN-gamma R1/CD119

Learn more about PTMs related to IFN-gamma R1/CD119.

Phosphorylation
Biotinylation
Reduction
Cleavage
Oxidation

Bioinformatics Tool for IFN-gamma R1/CD119

Discover related pathways, diseases and genes to IFN-gamma R1/CD119. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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