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HAF008). Specific bands were detected for HTRA2/Omi at approximately 36 and 49 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2." class="big_lightbox" target="_blank">
HAF007). A specific band was detected for HTRA2/Omi at approximately 35 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 4." class="big_lightbox" target="_blank">
NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed using our protocol for Fluorescent ICC Staining of Non-adherent Cells." class="big_lightbox" target="_blank">
HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).
![Western Blot HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/HTRA2_AF1458_Western_Blot_5114.jpg)
![Western Blot HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/images/antibody/HTRA2_MAB1458_Western_Blot_5969.jpg)
![Immunocytochemistry HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/HTRA2_AF1458_Immunocytochemistry_9924.jpg)
![Simple Western HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/16328.jpg)
![Western Blot HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1458_human-mouse-rat-htra2-omi-affinity-purified-polyclonal-ab-8220249504633.jpg)
![Western Blot HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1458_human-mouse-rat-htra2-omi-affinity-purified-polyclonal-ab-822024951145.jpg)
![Western Blot HTRA2/Omi Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1458_human-mouse-rat-htra2-omi-affinity-purified-polyclonal-ab-44202415425018.jpg)
![Immunocytochemistry HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/images/antibody/mab1458_human-htra2-omi-mab-clone-229926-immunocytochemistry-186202184143.jpg)
![Western Blot HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-western-blot-121220257453118.jpg)
![Immunocytochemistry/ Immunofluorescence HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-immunocytochemistry-immunofluorescence-12122025549587.jpg)
![Immunocytochemistry/ Immunofluorescence HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-immunocytochemistry-immunofluorescence-12122025750411.jpg)
![Western Blot HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-western-blot-1212202575304.jpg)
![Western Blot HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-western-blot-1212202574374.jpg)
![Immunocytochemistry/ Immunofluorescence HTRA2/Omi Antibody (229926) [Unconjugated]](http://images.novusbio.com/fullsize/mab1458_human-htra2-omi-mab-clone-229926-immunocytochemistry-immunofluorescence-1212202575043.jpg)
