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HTRA2/Omi Products

Antibodies
Proteins
Recombinant Human HTRA2/Omi P ...
Recombinant Human HTRA2/Omi Protei...
1458-HT
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
HTRA2/Omi Recombinant Protein ...
HTRA2/Omi Recombinant Protein Antigen
NBP2-58890PEP
Species: Hu
Applications: AC
HTRA2/Omi Recombinant Protein ...
HTRA2/Omi Recombinant Protein Antigen
NBP1-82482PEP
Species: Hu
Applications: AC

Description

HtrA2 (Omi) is a serine protease that plays a significant role in programmed cell death, or apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists predominantly as two isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. One way that HtrA2 induces apoptosis is by binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), and thereby inhibiting their caspase-inhibitory activity (2,3).

Bioinformatics

Product By Gene ID 27429
Alternate Names
  • High temperature requirement protein A2
  • HtrA serine peptidase 2
  • HTRA2
  • HtrA-like serine protease
  • Omi
  • OMIOmi stress-regulated endoprotease
  • PARK13EC 3.4.21.108
  • PRSS25
  • PRSS25serine, 25
  • Serine protease 25
  • serine protease HTRA2, mitochondrial
  • Serine proteinase OMI

Research Areas for HTRA2/Omi

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Mitochondrial-Mediated Pathway