HSD3B7 Products

Description

HSD3B7 codes for a protein with a length of 369 amino acids and a weight of approximately 41 kDa, with a shorter isoform with a length of 196 amino acids and a weight of approximately 21 kDa, and is a protein that plays a role in the biosynthesis of all classes of hormonal steroids, as it does not metabolize several different C steroids as substrates. It is also involved in bile acid synthesis from cholesterol. Current studies are being done on diseases and disorders relating to this gene including congenital bile acid synthesis defect, hepatitis, jaundice, cholesterol, tuberculosis, and neuronitis. HSD3B7 has also been shown to have interactions with PLSCR1, AKR1D1, CYP27A1, CYP39A1, and CYP7A1 in pathways such as the bile acid biosynthesis and metabolic pathways.

Bioinformatics

Entrez	80270 Human
Uniprot	NM_025193 Human NP_079469 Human NP_079469.2 Human Q9H2F3 Human
Product By Gene ID	80270
Alternate Names	3 beta-hydroxy-delta 5-C27-steroid oxidoreductase 3 beta-hydroxysteroid dehydrogenase type 7 3 beta-hydroxysteroid dehydrogenase type VII 3-beta-HSD VII 7-alpha-diol 3-beta-dehydrogenase C(27) 3-beta-HSD C(27)-3BETA-HSD Cholest-5-ene-3-beta EC 1.1.1.- EC 1.1.1.181 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7,3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase PFIC4 SDR11E3 short chain dehydrogenase/reductase family 11E, member 3