HS3ST3A1 Products

Description

HS3ST3A1 codes for a protein with a length of 406 amino acids and a weight of approximately 45 kDa, that is a sulfotransferase that utilizes PAPS to facilitate in the transfer of a sulfo group to a glucosamine on heparan sulfate, which causes the heparan sulfate to become enzyme-modified and acts as a binding receptor to HSV-1 and permits its entry, and is most abundant in the heart and placenta. Current studies are being done on diseases and disorders relating to this gene including recurrent respiratory papillomatosis, herpes simplex, and scoliosis. HS3ST3A1 has also been shown to have interactions with EXT1, EXT2, GLCE, GPC1, and GPC2 in pathways such as the heparan sulfate biosynthesis, metapathway biotransformation, Maroteauc-Lamy syndrome, metabolism, and Hunter syndrome pathways.

Bioinformatics

Entrez	9955 Human
Uniprot	NP_006033 Human NP_006033.1 Human
Product By Gene ID	9955
Alternate Names	3-OST-3A 3OST3A1heparan sulfate glucosamine 3-O-sulfotransferase 3A1,30ST3A1heparin-glucosamine 3-O-sulfotransferase EC 2.8.2 EC 2.8.2.30 h3-OST-3A heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 Heparan sulfate 3-O-sulfotransferase 3A1 Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1 HS3ST3A