HRD1 Products

Antibodies
HRD1 Antibody
HRD1 Antibody
NB100-2526
Species: Hu, Mu
Applications: WB, ICC/IF, IHC-P
Host: Rabbit Polyclonal
HRD1 Antibody
HRD1 Antibody
NBP1-89667
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HRD1 Antibody
HRD1 Antibody
NBP2-42519
Species: Hu
Applications: IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Lysates
HRD1 Overexpression Lysate (N ...
HRD1 Overexpression Lysate (Native)
NBL1-16660
Applications: WB
HRD1 Overexpression Lysate (N ...
HRD1 Overexpression Lysate (Native)
NBL1-16659
Applications: WB
HRD1 Overexpression Lysate (D ...
HRD1 Overexpression Lysate (Denatu...
H00084447-T02
Species: Hu
Applications: WB
Proteins
Recombinant Human HRD1 Protei ...
Recombinant Human HRD1 Protein
H00084447-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human HRD1 Protei ...
Recombinant Human HRD1 Protein
H00084447-P01
Species: Hu
Applications: WB, ELISA, PA
HRD1 Recombinant Protein Anti ...
HRD1 Recombinant Protein Antigen
NBP1-89667PEP
Species: Hu
Applications: AC
RNAi
HRD1 RNAi
HRD1 RNAi
H00084447-R02
Species: Hu
Applications: RNAi, RNAi SP
HRD1 RNAi
HRD1 RNAi
H00084447-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. It has been reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 84447
Alternate Names
  • EC 6.3.2
  • MGC40372
  • KIAA1810Synovial apoptosis inhibitor 1
  • HRD1EC 6.3.2.-
  • E3 ubiquitin-protein ligase synoviolin
  • synovial apoptosis inhibitor 1, synoviolin

Research Areas for HRD1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Ubiquitin Proteasome Pathway

PTMs for HRD1

Learn more about PTMs related to HRD1.

Ubiquitination
Phosphorylation
Glycosylation
Cleavage

Bioinformatics Tool for HRD1

Discover related pathways, diseases and genes to HRD1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HRD1 Blog Posts

Check out the latest blog posts on HRD1.
OS9: Taking proteins to the ER finish line
The OS9 protein is a lectin/glycoprotein that maintains endoplasmic reticulum (ER) quality control and ER-associated degradation (the so-called ERAD pathway) of newly synthesized proteins. It is essential for the recognition of terminally misfolded no...    Read more.
Read more HRD1 related blogs.