HOXB4 Products

Antibodies
HOXB4 Antibody
HOXB4 Antibody
NBP2-24561
Species: Hu, Mu, Rt, Bv, Fe, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
HOXB4 Antibody
HOXB4 Antibody
NBP2-24598
Species: Hu, Mu, Rt, Ca, Ze
Applications: IHC-P
Host: Rabbit Polyclonal
HOXB4 Antibody (3A2F2)
HOXB4 Antibody (3A2F2)
NBP2-37257
Species: Hu
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Lysates
HOXB4 Overexpression Lysate ( ...
HOXB4 Overexpression Lysate (Native)
NBL1-11671
Applications: WB
Proteins
HOXB4 Partial Recombinant Pro ...
HOXB4 Partial Recombinant Protein
H00003214-Q01
Species: Hu
Applications: WB, ELISA, PA
HOXB4 Recombinant Protein Ant ...
HOXB4 Recombinant Protein Antigen
NBP2-33833PEP
Species: Hu
Applications: AC
RNAi
HOXB4 RNAi
HOXB4 RNAi
H00003214-R01
Species: Hu

Description

Homebox transcription factors (Hox) are encoded by highly conserved developmental genes that are involved embryonic and early hematopoietic development. Specifically, Homeobox B4 (HoxB4) is a transcription factor encoded by HOXB4 gene and it is involved in the developmental regulation of specific positional identities on the anterior-posterior axis of cells. Like all members of HOX family, HoXB4 is abundantly expressed in primitive hematopoietic stem cell (HSC), but then decline with lineage-specific terminal differentiation (1). In HSC, stem cell self-renewal activity is regulated by USF1/2 binding to HoxB4, where binding possibly favors stem cell self-renewal instead of cell differentiation. Jun-B and Fra-1 has been linked as key mediators during cell proliferation and differentiation induced by HoxB4, which leads to increase expression of Cyclin D1 and G1 shortening (2).

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3214
Alternate Names
  • Homeobox protein Hox-2F
  • homeobox protein Hox-B4
  • Homeobox protein Hox-2.6
  • homeo box 2F
  • homeo box B4
  • HOX2FHOX2
  • HOX-2.6
  • homeobox B4

Bioinformatics Tool for HOXB4

Discover related pathways, diseases and genes to HOXB4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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