hnRNP U Products

Antibodies
hnRNP U Antibody
hnRNP U Antibody
NB100-2134
Species: Hu, Mu, Rt, Po, Bv, Ca, Eq, Ft, GP, Pm, Rb
Applications: WB, IHC, IHC-P, IP (-)
Host: Rabbit Polyclonal
hnRNP U Antibody
hnRNP U Antibody
NBP2-49290
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
hnRNP U Antibody (4G11)
hnRNP U Antibody (4G11)
H00003192-M03
Species: Hu, Mu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
hnRNP U Overexpression Lysate ...
hnRNP U Overexpression Lysate (Nat...
NBL1-11652
Applications: WB
Proteins
Recombinant Human hnRNP U Pro ...
Recombinant Human hnRNP U Protein
H00003192-Q01
Species: Hu
Applications: WB, ELISA, PA
hnRNP U Recombinant Protein A ...
hnRNP U Recombinant Protein Antigen
NBP2-48729PEP
Species: Hu
Applications: AC
hnRNP U Recombinant Protein A ...
hnRNP U Recombinant Protein Antigen
NBP2-49290PEP
Species: Hu
Applications: AC
RNAi
hnRNP U RNAi
hnRNP U RNAi
H00003192-R01
Species: Hu
Applications: RNAi, RNAi SP
hnRNP U RNAi
hnRNP U RNAi
H00003192-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

hnRNP U belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 3192
Alternate Names
  • p120
  • hnRNP U
  • SAFA
  • U21.1
  • p120 nuclear protein
  • HNRPU
  • heterogeneous nuclear ribonucleoprotein U
  • Scaffold attachment factor A
  • SAF-AhnRNPU
  • pp120
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

Research Areas for hnRNP U

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Cellular Markers

Bioinformatics Tool for hnRNP U

Discover related pathways, diseases and genes to hnRNP U. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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