HGK/MAP4K4 Products

Antibodies
HGK/MAP4K4 Antibody [Unconjug ...
HGK/MAP4K4 Antibody [Unconjugated]
AF6027
Species: Hu
Applications: WB
Host: Goat Polyclonal
HGK/MAP4K4 Antibody (4A5)
HGK/MAP4K4 Antibody (4A5)
H00009448-M07
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
HGK/MAP4K4 Antibody
HGK/MAP4K4 Antibody
NBP1-58853
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HGK/MAP4K4 Overexpression Lys ...
HGK/MAP4K4 Overexpression Lysate (...
NBL1-12861
Applications: WB
Proteins
Recombinant Human HGK/MAP4K4 ...
Recombinant Human HGK/MAP4K4 Protein
H00009448-Q01
Species: Hu
Applications: WB, ELISA, PA
HGK/MAP4K4 Recombinant Protei ...
HGK/MAP4K4 Recombinant Protein Ant...
NBP1-84663PEP
Species: Hu
Applications: AC
RNAi
HGK/MAP4K4 RNAi
HGK/MAP4K4 RNAi
H00009448-R05
Species: Hu
Applications: RNAi, RNAi SP
HGK/MAP4K4 RNAi
HGK/MAP4K4 RNAi
H00009448-R04
Species: Hu
Applications: RNAi, RNAi SP
HGK/MAP4K4 RNAi
HGK/MAP4K4 RNAi
H00009448-R06
Species: Hu
Applications: RNAi, RNAi SP

Description

MAP4K4 is encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 9448
Alternate Names
  • EC 2.7.11.1
  • EC 2.7.11
  • MEKKK 4
  • hepatocyte progenitor kinase-like/germinal center kinase-like kinase
  • MEK kinase kinase 4
  • MAPK/ERK kinase kinase kinase 4
  • HPK/GCK-like kinase HGK
  • KIAA0687
  • Nck-interacting kinase
  • FLH21957
  • NIKFLJ90111
  • HGKFLJ20373
  • FLJ10410
  • mitogen-activated protein kinase kinase kinase kinase 4

Research Areas for HGK/MAP4K4

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase

PTMs for HGK/MAP4K4

Learn more about PTMs related to HGK/MAP4K4.

Phosphorylation
Methylation
Oxidation

Bioinformatics Tool for HGK/MAP4K4

Discover related pathways, diseases and genes to HGK/MAP4K4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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