HAND1 Products

Description

HAND1 is encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq]

Bioinformatics

Entrez	9421 Human
Uniprot	NM_004821 Human NP_004812.1 Human O96004 Human
Product By Gene ID	9421
Alternate Names	BHLHA27 bHLHa27heart- and neural crest derivatives-expressed protein 1 Class A basic helix-loop-helix protein 27 eHAND eHand EHAND Extraembryonic tissues, heart, autonomic nervous system and neural crestderivatives-expressed protein 1 heart and neural crest derivatives expressed 1 Hxt Thing1

Diseases related to HAND1

Discover more about diseases related to HAND1.

Crest Syndrome
Heart Diseases
Malignant Neoplasms
Congenital Heart Disease
Congenital Heart Defects
Hypoplasia
Neoplasms
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Heart Failure
Carcinogenesis
Nervousness
Hypoplastic Left Heart Syndrome
Tissue Adhesions
Tumor Angiogenesis
Congenital Abnormality
Hypertrophy
Cell Invasion
Lymphohistiocytosis, Hemophagocytic
Cardiac Hypertrophy

Pathways for HAND1

View related products by pathway and learn more about each of the pathways below.

Heart Development
Cell Differentiation
Methylation
Dna Methylation
Pathogenesis
Cell Proliferation
Cell Cycle
Heart Morphogenesis
Osteoblast Differentiation
Trophoblast Giant Cell Differentiation
Angiogenesis
Cell Adhesion
Limb Development
Transport
Gene Silencing
Stem Cell Differentiation
Neurogenesis
Secretion
Vasculogenesis
Cell Division

PTMs for HAND1

Learn more about PTMs related to HAND1.

Methylation
Phosphorylation
Demethylation
Deacetylation
Acetylation
Ubiquitination

Bioinformatics Tool for HAND1

Discover related pathways, diseases and genes to HAND1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.