H1FOO Products

Description

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. The H1FOO gene encodes a H1 Histone Family, member O, oocyte-specific protein. One isoform is 346 amino acids long at 35 kDA while isoform 2 is 207 amino acids long at 21 kDA. The replacement of H1c with H1FOO may be critical to nuclear remodeling as greater mobility of H1FOO increases stability of the embryonic chromatin structure. H1FOO participates in histone modification and cell cycle chromosome condensation in prometaphase. H1FOO has been studied in regards to premature ovarian failure.

Bioinformatics

Entrez	132243 Human 80838 Mouse
Uniprot	AAH47943 Human AAH47943.1 Human Q8IZA3 Human
Product By Gene ID	132243
Alternate Names	H1 histone family, member O, oocyte-specific H1OO histone H1oo MGC50807 Oocyte-specific histone H1 Oocyte-specific linker histone H1 OSH1 osH1

Research Areas for H1FOO

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Phospho-Specific